Microcompartments in prokaryotes: carboxysomes and related polyhedra.

نویسندگان

  • G C Cannon
  • C E Bradburne
  • H C Aldrich
  • S H Baker
  • S Heinhorst
  • J M Shively
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Functions, compositions, and evolution of the two types of carboxysomes: polyhedral microcompartments that facilitate CO2 fixation in cyanobacteria and some proteobacteria.

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CO2 fixation kinetics of Halothiobacillus neapolitanus mutant carboxysomes lacking carbonic anhydrase suggest the shell acts as a diffusional barrier for CO2.

The widely accepted models for the role of carboxysomes in the carbon-concentrating mechanism of autotrophic bacteria predict the carboxysomal carbonic anhydrase to be a crucial component. The enzyme is thought to dehydrate abundant cytosolic bicarbonate and provide ribulose 1.5-bisphosphate carboxylase/oxygenase (RubisCO) sequestered within the carboxysome with sufficiently high concentrations...

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BACKGROUND The carboxysome is a bacterial microcompartment that consists of a polyhedral protein shell filled with ribulose 1,5-bisphosphate carboxylase/oxygenase (RubisCO), the enzyme that catalyzes the first step of CO2 fixation via the Calvin-Benson-Bassham cycle. METHODOLOGY/PRINCIPAL FINDINGS To analyze the role of RubisCO in carboxysome biogenesis in vivo we have created a series of Hal...

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عنوان ژورنال:
  • Applied and environmental microbiology

دوره 67 12  شماره 

صفحات  -

تاریخ انتشار 2001